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Clinical calculator summary

Glasgow Prognostic Score (GPS)

The Glasgow Prognostic Score is an inflammation-based prognostic system using serum CRP and albumin levels to predict survival across multiple cancer types.

Evidence-based context for fast calculator use

Purpose:
Assess systemic inflammatory response as a prognostic indicator in cancer
Population:
Cancer patients (validated across multiple tumour types)
Factors:
C-reactive protein (CRP) >10 mg/L, Albumin <35 g/L
Reference:
McMillan, Cancer Treatment Reviews 2013
HomeGlasgow Prognostic Score (Standard)
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Glasgow Prognostic Score (Standard)

mg/L
g/L

Clinical Context & Background

The standard Glasgow Prognostic Score (GPS) combines C-reactive protein (CRP) and albumin to assess systemic inflammation. It is a strong prognostic factor for survival in various advanced cancers. (Note: The Modified GPS is also available in this app).
Primary Source EvidenceForrest LM, McMillan DC, McArdle CS, Angerson WJ, Dunlop DJ. Evaluation of cumulative prognostic scores based on the systemic inflammatory response in patients with inoperable non-small-cell lung cancer. Br J Cancer. 2003;89(6):1028-1030.
Formula Logic
Score 0-2 based on CRP > 10 mg/L and Albumin < 35 g/L.

Reference Data

ScoreCriteriaPrognosis
0CRP ≤ 10 mg/L AND Albumin ≥ 35 g/LGood Prognosis
1CRP ≤ 10 mg/L AND Albumin < 35 g/L OR CRP > 10 mg/L AND Albumin ≥ 35 g/LIntermediate Prognosis
2CRP > 10 mg/L AND Albumin < 35 g/LPoor Prognosis

Clinical Workflow

Use, Interpret, And Continue The Patient Pathway

Expand for workflow guidance, limitations, examples, and related next steps.

When To Use

  • Use Glasgow Prognostic Score (Standard) when glasgow Prognostic Score combines CRP and albumin to assess systemic inflammation and estimate cancer prognosis for treatment planning.
  • Confirm that the patient, diagnosis, disease phase, and available inputs match the cited model before calculation.

How To Interpret

  • Interpret the displayed result using the calculator-specific formula and reference table, spanning 0 through 2.
  • A boundary result should prompt input verification and clinical review rather than false precision.

What To Do Next

  • Integrate the result with diagnosis, disease burden, organ function, frailty, treatment intent, medicines, and patient goals.
  • Document the inputs, result, timing, and clinical context so the assessment can be reproduced.

Limitations

  • General oncology tools measure one domain and should not become a universal treatment-eligibility rule.
  • The result supports clinician judgment and does not independently determine treatment.

Validated Population

patients whose general oncology assessment matches the intended use of the selected score

How to apply this result

For a representative case, verify C-Reactive Protein, Albumin, calculate the result, and confirm that its classification matches the highlighted reference band before continuing the disease-specific pathway.

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Frequently Asked Questions

When should Glasgow Prognostic Score (Standard) be used?

Use it for patients whose general oncology assessment matches the intended use of the selected score when all required inputs and the intended clinical setting are confirmed.

Can Glasgow Prognostic Score (Standard) determine treatment by itself?

No. Interpret the result with the cited evidence, complete clinical assessment, current guidelines, and patient-specific goals.

Evidence-based oncology decision support. Verify with clinical guidelines.