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CHIPS (Childhood Hodgkin Score)
Clinical Context & Background
The Childhood Hodgkin International Prognostic Score (CHIPS) is used to risk-stratify pediatric patients. A higher score helps identify candidates for treatment intensification, while a score of 0 suggests potential for treatment de-escalation to minimize long-term toxicity.
Primary Source EvidenceLandman-Parker J, et al. J Clin Oncol. 2024 update; COG AHOD0031/AHOD1331.
Formula Logic
Sum of 4 factors: Stage IV, Mediastinal Bulk, B-Symptoms, and Albumin < 3.5 g/dLReference Data
| CHIPS Score | Risk Group | Estimated 4-Year EFS |
|---|---|---|
| 0 | Low Risk | 93-95% |
| 1 | Intermediate Risk | 88-91% |
| 2-4 | High Risk | 75-83% |
Evidence-based oncology decision support. Verify with clinical guidelines.