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HKLC Staging System

Clinical Context & Background

The HKLC (Hong Kong Liver Cancer) staging system identifies patients with intermediate and locally advanced HCC who may benefit from more aggressive treatments (Resection or TACE) compared to BCLC recommendations. It classifies patients into 5 main stages (I to IV).
Formula Logic
Algorithmic classification based on PS, Child-Pugh, Tumor Size/Number, Vascular Invasion, and Metastasis.

Reference Data

StageDescriptionRecommended Treatment
Stage IEarly (Solitary ≤5cm or 2-3 ≤3cm)Resection / Ablation
Stage IIaIntermediate (Solitary >5cm)Resection
Stage IIbIntermediate (Multinodular)TACE
Stage IIIaLocally Advanced (PS 1 or CP B)TACE
Stage IIIbLocally Advanced (Vascular Inv)TACE (or Resection)
Stage IVaMetastaticSystemic Therapy
Stage IVbTerminal (PS >1 or CP C)Supportive Care

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Evidence-based oncology decision support. Verify with clinical guidelines.