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IGCCCG Risk Classification (2021 Update)
Clinical Context & Background
The International Germ Cell Cancer Collaborative Group (IGCCCG) classification stratifies patients with metastatic Non-Seminoma and Seminoma into Good, Intermediate, and Poor risk groups.
The 2021 Update re-validated the original criteria with modern data, showing significantly improved survival rates compared to the 1997 cohort.
Formula Logic
Risk based on Primary Site, Markers (AFP, hCG, LDH), and Mets location.Reference Data
| Risk Group | 5-Year Survival (2021 Update) | Treatment (Standard) |
|---|---|---|
| Good Risk | 96% (Non-Sem) / 95% (Sem) | BEP x 3 or EP x 4 |
| Intermediate | 89% (Non-Sem) / 88% (Sem) | BEP x 4 |
| Poor Risk | 67% (Non-Sem) | BEP x 4 or VIP x 4 |
Related Tools
Evidence-based oncology decision support. Verify with clinical guidelines.