IMDC (Heng) Risk Criteria for Metastatic RCC

The IMDC criteria stratify metastatic renal cell carcinoma patients into favourable, intermediate, or poor risk groups using six clinical and laboratory factors, guiding first-line systemic therapy selection.

Purpose:

Risk-stratify metastatic RCC patients for first-line treatment selection

Population:

Patients with metastatic renal cell carcinoma initiating systemic therapy

Factors:

KPS <80%, Time from diagnosis to treatment <1 year, Haemoglobin below normal, Corrected calcium above normal, Neutrophils above normal, Platelets above normal

Reference:

Heng et al., JCO 2009