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Diagnosis-Specific GPA (Brain Mets)
Clinical Context & Background
The Diagnosis-Specific Graded Prognostic Assessment (DS-GPA) is the modern standard for brain metastasis prognosis. This tool uses the updated Lung-molGPA (2017), Melanoma-molGPA (2017), Breast GPA (2020 Update), and Renal/GI GPA models.
Formula Logic
Sum of points varies by Primary Site.Reference Data
| GPA Score | Median Survival (Months) |
|---|---|
| 0 - 1.0 | Poor (~ 3-6 mo) |
| 1.5 - 2.0 | Intermediate (~ 9-13 mo) |
| 2.5 - 3.0 | Good (~ 15-25 mo) |
| 3.5 - 4.0 | Excellent (> 30 mo) |
Evidence-based oncology decision support. Verify with clinical guidelines.