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CPS+EG Score
Clinical Context & Background
The Clinical-Pathologic Stage + Estrogen/Grade (CPS+EG) staging system improves prognostic stratification for patients with breast cancer treated with neoadjuvant chemotherapy. It incorporates both the presenting clinical stage and the final pathologic stage, along with biologic factors.
Formula Logic
Score = Clinical Stage + Pathologic Stage + ER Status + Nuclear GradeReference Data
| Total Score | 5-Year Distant Metastasis-Free Survival (DMFS) |
|---|---|
| 0 | > 90% |
| 1 | ~ 85-90% |
| 2 | ~ 75-85% |
| 3 | ~ 60-70% |
| 4 | ~ 45-55% |
| 5 - 6 | < 30% |
Evidence-based oncology decision support. Verify with clinical guidelines.